Urine concentrations changes of cysteinyl leukotrienes in non-obese children with obstructive sleep apnea undergoing adenotonsillectomy.

In this study, the authors measure urinary levels of Cysteine Leukotrienes (CysLT) in children with documented severe OSAS by PSG before and after adenotonsillectomy. CysLT has been previously implicated in the development of adenotonsillar hypertrophy and pediatric OSAS. Children with residual OSAS were excluded. A total of 24 children were included for analysis. The authors suggest further studies in order to  determine CysLT as valid biomarker for the presence of OSA in children.