Predictors of Long-Term Adherence to Continuous Positive Airway Pressure in Patients with Obstructive Sleep Apnea and Cardiovascular Disease

“Poor adherence to CPAP commonly affects therapeutic response in those affected by obstructive sleep apnea (OSA). Among 1,121 participants in the SAVE study, aged 45–75 years with co-occurring moderate-to-severe OSA and cardiovascular disease, who were randomized to CPAP therapy, greater early adherence was most predictive of higher long-term adherence at 24 months. Other positive predictor variables were higher CPAP pressure, very loud snoring and country. While other variables were significant univariate predictors, they did not retain overall significance and explained only a small component of the variation in adherence. These data may be utilized to better target efforts to improve CPAP adherence.”