Optogenetic Stimulation of Melanin Concentrating Hormone (MCH) Neurons Increases Sleep

MCH stimulation increased both non-REM and REM sleep against a very strong circadian waking drive. This has significant potential for the insomnia associated with shift-work and jet-lag, conditions where a strong waking drive blocks sleep onset

http://www.ncbi.nlm.nih.gov/pubmed/23785141