Electrocardiogram-Based Sleep Analysis for Sleep Apnea Screening and Diagnosis

This study aimed to first evaluate the reliability of cardiopulmonary coupling analysis for the detection of OSA by comparing with polysomnography (PSG) derived sleep outcomes. PSG data from 205 participants was obtained for the evaluation of cardiopulmonary coupling by ECG regarding the detection of OSA. Automated CPC analyses were based on ECG signals only. Respiratory event index (REI) derived from CPC and apnea-hypopnea index (AHI) derived from PSG were compared for agreement tests. Results showed that cardiopulmonary coupling -REI positively correlated with PSG-AHI (r = 0.851, p < 0.001). Findings indicate that in the future ECG signals may potentially serve as screening tools for OSA.