Posted in
Basic Research, Literature Updates
Posted:
May 1, 2014
Authors: Tarasiuk A, Levi A, Berdugo-Boura N, Yahalom A, Segev Y.
Published: Sleep. 2014 May 1;37(5):987–98.
In upper airway obstruction animals, enhanced orexin secretion, while crucially important for respiratory homeostasis maintenance, is also responsible for chronic partial sleep loss, as well as considerable impairment of energy metabolism and growth.
http://www.ncbi.nlm.nih.gov/pubmed/24790278
Posted in
Basic Research, Literature Updates
Posted:
May 1, 2014
Authors: Kuo TH, Williams JA
Published: Sleep. 2014 May 1;37(5):859–69.
Using a Drosophila model the authors found that acute sleep deprivation elevated NFκB-dependent activity, increased post-infection sleep, and improved survival during bacterial infection.
http://www.ncbi.nlm.nih.gov/pubmed/24790264
Posted in
ICU, Literature Updates
Posted:
May 1, 2014
Authors: McKinley S, Fine M, Elliott R, Elliott D.
Published: J Psychosis Res. 2013 Dec; 75(6): 539–45
In this study, the authors attempted to asses patient’s self reported sleep quality in the ICU, after ICU and pre hospital discharge and two to six months after hospital discharge. They wanted to determine if pre-hospital insomnia, experiences in intensive care, quality of life and psychological health are associated with sleep disruption six months after hospital discharge. Two hundred and twenty two patients completed the survey. For more than half of the patients, sleep was a “significant” issue 6 months after ICU treatment. The authors suggested targeting potentially modifiable risk factors in recovery programs.
http://www.ncbi.nlm.nih.gov/pubmed/24290043
Posted in
ICU, Literature Updates
Posted:
May 1, 2014
Authors: Surani S, Hesselbacher S, Guntupalli B, Surani S, Subramanian S
Published: J Patient Saf. 2014 Feb 11.
In this very interesting study, the authors evaluated sleep quality in nurses and evaluate how setting (ICU vs. floor) and time of shift (day vs. night) impacted measures of sleep quality. The authors discovered that a significant number of inpatient nurses have impaired sleep quality, excessive sleepiness, and abnormal fatigue. They stated that these findings might place these nurses at a greater risk of making medical errors and harming patients. They found these problems to be more pronounced in night shift workers and that floor and day shift nurses performed better on some tasks than ICU and night shift nurses. This study is important in that it reminds us that in the ICU, sleep deprivation amongst the staff may also have serious complications that are separate from sleep deprivation in patients.
http://www.ncbi.nlm.nih.gov/pubmed/24522213
Posted in
ICU, Literature Updates
Posted:
May 1, 2014
Authors: Esquinas AM, Papadakos PJ, Schwartz AR
Published: Crit Care Med. 2014 Jan;42(1):e82-3
In this interesting letter to the editor, the authors comment on Comparison of Sleep Quality With Mechanical Versus Spontaneous Ventilation During Weaning of Critically Ill Tracheostomized Patients that appeared in Crit Care Med (2013;41:1637–1644). The authors agree that poor sleep may affect weaning from mechanical ventilation. However, the authors point out potential limitations in the cross-over design and ways some patients were treated with mechanical ventilation. For those who read the article by Roche-Campo F, this letter will serve to further the discussion on sleep mechanical ventilation and weaning.
http://www.ncbi.nlm.nih.gov/pubmed/24346550
Posted in
ICU, Literature Updates
Posted:
May 1, 2014
Authors: Tam rat R, Huynh-Le MP, Goyal M.
Published: J Gen Intern Med. 2014 May;29(5):788–95.
This study was not actually an evaluation of ICU patients as the names implies. However, many of the findings will be of interest to the ICU physician. The authors sought to indentify non-pharmacologic interventions that are effective in improving sleep quality and quantity on non-ICU patients. The authors indentified 13 intervention studies with 1154 participants. Unfortunately, there was insufficient to low strength of evidence to recommend any non-pharmacologic therapy. The study does list some interventions that have been tried that the reader may find of interest in some of the less acute ICU patients.
http://www.ncbi.nlm.nih.gov/pubmed/24113807
Posted in
Clinical Pediatric, Literature Updates
Posted:
May 1, 2014
Authors: Alexander NS, Schroeder JW Jr.
Published: Pediatr Clin North Am. 2013 Aug;60(4):827–40.
Over the last decade, significant advancements have been made in the evidence-based management of pediatric OSAS. This article focuses on the current understanding of this disease, its management, and related clinical practice guidelines.
http://www.ncbi.nlm.nih.gov/pubmed/23905822
Posted in
Clinical Pediatric, Literature Updates
Posted:
May 1, 2014
Authors: Ng DK, Chan CH.
Published: Pediatr Neonatol. 2013 Apr;54(2):82–7.
The normal values of obstructive apnea, mixed apnea, and central apnea are well established for neonates and infants. With these normal values, sleep polysomnography study should be routinely used to quantify the severity of breathing disorders during sleep in those neonates at risk for these disorders.
http://www.ncbi.nlm.nih.gov/pubmed/23590951
Posted in
Clinical Pediatric, Literature Updates
Posted:
May 1, 2014
Authors: Chang L, Wu J, Cao L.
Published: Int J Pediatr Otorhinolaryngol. 2013 Mar;77(3):365–71.
Observable apnea during sleep was an independent positive predictive factor for OSA in children. A child with observable apnea during sleep should be referred to a special sleep laboratory for PSG diagnosis. When the total score is 3 or 4 based on a combination of symptoms and ODI, OSA can be diagnosed and the child should be referred to a sleep pediatrician for appropriate intervention.
http://www.ncbi.nlm.nih.gov/pubmed/23246417
Posted in
Clinical Pediatric, Literature Updates
Posted:
May 1, 2014
Authors: Kahlke PE, Witmans MB, Alabdoulsalam T, Young R, MacLean JE, Mandhane PJ.
Published: Sleep Med. 2013 Feb;14(2):177–82.
The high sensitivity between full-night and 4-h PSG supports the use of 4-h PSG in children 24monthsand under, especially those ⩽6months of age.
http://www.ncbi.nlm.nih.gov/pubmed/23266107