Posted in
Basic Research, Literature Updates
Posted:
July 14, 2017
Contributors: Susana Vacas
Published: Sleep. 2017 Apr 1;40(4).
Authors: Machida M, Wellman LL, Fitzpatrick Bs ME, Hallum Bs O, Sutton Bs AM, Lonart G, Sanford LD.
“Glutamatergic cells in BLA can modulate the effects of stress on REM and can mediate effects of fear memory on sleep that can be independent of behavioral fear.”
https://www.ncbi.nlm.nih.gov/pubmed/28199723
Posted in
Literature Updates, Sedation
Posted:
July 14, 2017
Contributors: Susana Vacas
Published: Front Neural Circuits. 2017 Jun 20;11:44.
Authors: Mashour GA, Hudetz AG.
A very elegant review on the controversy of the precise mechanisms of anesthetic-induced unconsciousness and how levels and contents of consciousness interact to generate subjective experience and what this implies for the mechanisms of anesthetic-induced unconsciousness.
https://www.ncbi.nlm.nih.gov/pubmed/28676745
Posted in
ICU, Literature Updates
Posted:
July 14, 2017
Contributors: Susana Vacas
Published: Crit Care Res Pract. 2017;2017:7010854.
Authors: Boyko Y, Holst R, Jennum P, Oerding H, Nikolic M, Toft P.
In this pilot descriptive study, melatonin secretion pattern in conscious, critically ill patients on mechanical ventilation was found to follow a diurnal but phase-delayed curve. Remifentanil infusion did not affect melatonin secretion but was associated with lower risk of atypical sleep.
https://www.ncbi.nlm.nih.gov/pubmed/28584667
Posted in
Clinical Pediatric, Literature Updates
Posted:
July 14, 2017
Contributors: Kimmo Murto
Published: Int J Pediatr Otorhinolaryngol. 2016 Apr;83:205-10.
Authors: Song SA, Tolisano AM, Cable BB, Camacho M.
“This meta-analysis found an improvement in neurocognitive function and IQ after pediatric adenotonsillectomy, especially in pre-school aged children. However, this must be interpreted with caution as only three studies were performed in pre-school aged children. The decreased effectiveness in older children suggests possibly a threshold age when neurocognitive deficits become irreversible.”
http://www.ncbi.nlm.nih.gov/pubmed/26968078
Posted in
Clinical Pediatric, Literature Updates
Posted:
July 14, 2017
Contributors: Kimmo Murto
Published: Chest. 2016 Apr;149(4):999-1010.
Authors: Koren D, Gozal D, Bhattacharjee R, Philby MF, Kheirandish-Gozal L.
“T&A improved insulin resistance and high density lipoprotein, and residual OSA is predicted by baseline fasting plasma insulin and BMI z score, indicating a causal relationship; however, following T&A, residual metabolic dysfunction related to underlying adiposity rather than remaining sleep-disordered breathing.”
http://www.ncbi.nlm.nih.gov/pubmed/26447773
Posted in
Clinical Pediatric, Literature Updates
Posted:
July 14, 2017
Contributors: Kimmo Murto
Published: Int J Pediatr Otorhinolaryngol. 2016 Mar;82: 54-7.
Authors: Arachchi S, Armstrong DS, Roberts N, Baxter M, McLeod S, Davey MJ, Nixon GM.
“In a cohort of children with known moderate-severe OSA, post-operative AE after AT were all managed in the high acuity unit (HAU). Post-operative care in HAU provides safe and effective care for high-risk children post-AT, minimizing admissions to ICU.”
http://www.ncbi.nlm.nih.gov/pubmed/26857316
Posted in
Clinical Pediatric, Literature Updates
Posted:
July 14, 2017
Contributors: Kimmo Murto
Published: Eur J Pediatr. 2016 Feb;175(2):211-20
Authors: Su MS, Zhang HL, Cai XH, Lin Y, Liu PN, Zhang YB, Hu WZ, Li CC, Xiao YF.
“We demonstrated differential risk factors for OSA in obese children, which suggest that a different mechanism may be involved in OSA development in preschool and school-age children.”
http://www.ncbi.nlm.nih.gov/pubmed/26316318
Posted in
Clinical Pediatric, Literature Updates
Posted:
July 14, 2017
Contributors: Kimmo Murto
Published: Int J Oral Maxillofac Surg. 2016 Feb;45 (2):167-9.
Authors: Inverso G, Brustowicz KA, Katz E, Padwa BL.
“Given that 56.4% of patients with syndromic craniosynostosis (SCS) are symptomatic and that 74.2% of these symptomatic patients have OSA, it is recommended that a screening level I polysomnography be part of the clinical care for all patients with SCS.”
http://www.ncbi.nlm.nih.gov/pubmed/26602951
Posted in
Clinical Pediatric, Literature Updates
Posted:
July 14, 2017
Contributors: Kimmo Murto
Published: Sleep Med Rev. 2016 Feb;25: 31-9.
Authors: Honaker SM, Meltzer LJ.
“Despite the high prevalence of pediatric sleep problems in primary care, rates of screening and management are low. Primary care providers receive minimal sleep training and have resulting gaps in knowledge and confidence.”
http://www.ncbi.nlm.nih.gov/pubmed/26163054
Posted in
Clinical Pediatric, Literature Updates
Posted:
July 14, 2017
Contributors: Kimmo Murto
Published: Eur Respir J. 2016 Jan; 47(1):69-94.
Authors: Kaditis AG, Alonso Alvarez ML, Boudewyns A, Alexopoulos EI, Ersu R, Joosten K, Larramona H, Miano S, Narang I, Trang H, Tsaoussoglou M, Vandenbussche N, Villa MP, Van Waardenburg D, Weber S, Verhulst S.
“This document summarises the conclusions of a European Respiratory Society Task Force on the diagnosis and management of obstructive sleep disordered breathing (SDB) in childhood and refers to children aged 2-18 years.”
http://www.ncbi.nlm.nih.gov/pubmed/26541535