Dexmedetomidine vs Propofol-Remifentanil Conscious Sedation for Awake Craniotomy: A Prospective Randomized Controlled Trial

Another successful application of dexmedetomidine as a sedative agent in the clinical setting, in this case for awake craniotomies. Dexmedetomidine exhibits similar efficacy as the combination of propofol and remifentanil but with a significantly less number of respiratory depression related events.

https://www.ncbi.nlm.nih.gov/pubmed/27099154