Association of Adenotonsillectomy With Asthma Outcomes in Children: A Longitudinal Database Analysis

Bhattacharjee and Mokhlesi examined the 2003–2010 MarketScan database. MarketScan database provides access to a large database of over 25 million children capturing reimbursements from the health private insurance plans and payments accrued by patients including inpatient and outpatient settings as well as pharmacy expenses. Children were identified for a study period between January 1, 2003, and December 31, 2010. A total of 13,506 children with asthma in the United States who underwent adenotonsillectomy (AT). Asthma outcomes during 1 y preceding AT were compared to those during 1 y following AT. In addition, 27,012 age-, sex-, and geographically matched children with asthma without AT were included to examine asthma outcomes among children without known adenotonsillar tissue morbidity. AT was associated with significant improvements in several asthma outcomes such as asthma exacerbation, ER visits, hospitalizations, reduction in prescription refills for bronchodilators, inhaled corticosteroids and systemic corticosteroids. In contrast, there were no significant reductions in these outcomes in children with asthma who did not undergo AT over an overlapping follow-up period.