Independent Association Between Nocturnal Intermittent Hypoxemia and Metabolic Dyslipidemia

In a sample of 2,018 patients who underwent measurement of fasting lipid levels and nocturnal recording for assessment of obstructive sleep apnea, total cholesterol and LDL were not associated with the oxygen desaturation index. However, nocturnal intermittent hypoxemia and OSA severity were associated with higher triglycerides and lower HDL-C, independent of confounders. This may provide a mechanism through which OSA is associated with cardiovascular risk.

Associations Between Change in Sleep Duration and Inflammation: Findings on C-Reactive Protein and Interleukin 6 in the Whitehall II Study

In a sample of 5,003 midlife men and women, shorter sleep (< 5 hours per night) was associated with higher levels of CRP and IL-6 and in longitudinal analyses, a greater increase in sleep duration was associated with a significant 5-year increase in CRP and IL-6.

Sleep Apnea and Total Joint Arthroplasty Under Various Types of Anesthesia: A Population-Based Study of Perioperative Outcomes

The authors “analyzed data from approximately 400 hospitals in the United States. Perioperative outcomes were compared between patients receiving general, neuraxial, or combined neuraxial-general anesthesia. “They concluded that “neuraxial anesthesia may convey benefits in the perioperative outcome of SA patients undergoing joint arthroplasty.”

Sleep–Disordered Breathing and Postoperative Outcomes After Bariatric Surgery: Analysis of the Nationwide Inpatient Sample

In this large nationally representative sample, despite the increased association of SDB/OSA with postoperative cardiopulmonary complications, the diagnosis of SDB/OSA was negatively, rather than positively, associated with in-hospital mortality and resource use.

Development and Validation of a Score for Prediction of Postoperative Respiratory Complications

The authors developed and validated a score for the prediction of postoperative respiratory complications, a simple, 11-point score that can be used preoperatively by anesthesiologists to predict severe postoperative respiratory complications. Independent predictors for reintubation were: American Society of Anesthesiologist Score 3 or more, emergency surgery, high-risk surgical service, history of congestive heart failure, and chronic pulmonary disease.