Prevalence of primary open-angle glaucoma among patients with obstructive sleep apnea

A “convenience sample” referred by Sleep Medicine for oral appliances because of continuous positive airway pressure intolerance was analyzed. The investigators determined the aggregate prevalence of the 3 POAG subtypes-“classic” open-angle glaucoma (COAG), normal-tension glaucoma (NTG), and open-angle glaucoma suspect (OAGS)-among the index population and compared it with that of same hospital’s general population. Furthermore, associations between OSA severity levels (apnea-hypopnea index [AHI]) and POAG subtypes were investigated. Results showed that among the study sample of 225 patients with OSA, 20.9% had POAG, which was significantly higher than the POAG prevalence rate among the medical center’s general population at 2.5%, (Pā€‰<ā€‰.00001). Severity of the breathing disorder measured by AHI, however failed to identify a significant correlation to any POAG subtype (Pā€‰>ā€‰.05).

The significantly increased prevalence of POAG among OSA patients suggests the need for preoperative consultations from an ophthalmologist to determine eye health and possibly an anesthesiologist to avoid potential vision loss.