Predictors of Delirium After Cardiac Surgery in Patients with Sleep-Disordered Breathing

Delirium ranks among the most common complications after cardiac surgery. This prospective observational study investigated risk factors for delirium in 141 patients undergoing cardiac surgery.

The presence of OSA was assessed with a portable sleep disordered breathing monitor the night before surgery. Delirium was examined with the validated Confusion Assessment Method for Intensive Care Units on the day of extubation and for a maximum of 3 days.

Multivariable logistic regression analysis showed that delirium was independently associated with age ≥70 years (OR 5.63, CI 1.79-17.68), central sleep apnea (OR 4.99, CI 1.41-17.69), and heart failure (OR 3.3, CI 1.06-10.35). Length of hospital stay, and time spent in the ICU/IMC were significantly longer for patients with delirium. In conclusion, central sleep apnea was independently associated with delirium amongst other established risk factors.