Mechanisms Mediating Effects of Nitric Oxide on Perifornical Lateral Hypothalamic Neurons

Nitric oxide is a gaseous neurotransmitter that has been implicated in the regulation of sleep. In this study the authors investigated contributions of adenosinergic, GABAergic, and sGC-cGMP signaling mechanisms in mediating nitrergic influences on a major wake-promoting structure, the perifornical-lateral hypothalamic area neurons.