Evidence for Neuronal Desynchrony in the Aged Suprachiasmatic Nucleus Clock

Aging leads to a deterioration of circadian rhythms in physiology and behavior. These authors analyzed circadian rhythms in the course of aging on different levels of organization. They were able to show that aging affects the suprachiasmatic nucleus at the network level organization as opposed to the single cell membrane deterioration “theory”.

http://www.ncbi.nlm.nih.gov/pubmed/22539850