Clinical Adult Literature Updates from November 2015

Impact of Obstructive Sleep Apnea Syndrome on Cognition in Early Postmenopausal Women

Early postmenopausal women who were not on hormone replacement therapy completed a REDCap survey on demographics and risk factor, Berlin questionnaire and Mail-in Cognitive Function Screening Instrument (MCFSI) score to assess cognitive impairment. Early postmenopausal women at high risk for OSAS reported more cognitive impairment than those at low risk for OSAS.

http://www.ncbi.nlm.nih.gov/pubmed/26385776

Evidence of Neurodegeneration in Obstructive Sleep Apnea: Relationship Between Obstructive Sleep Apnea and Cognitive Dysfunction in the Elderly

This review discusses the pathological commonalities between OSA and Alzheimer’s Disease. The potential prevention of cognitive decline in middle-aged and elderly persons with treatment of OSA is reviewed.

http://www.ncbi.nlm.nih.gov/pubmed/26301370

Chronic Widespread Musculoskeletal Pain in Patients with Obstructive Sleep Apnea Syndrome and the Relationship Between Sleep Disorder and Pain Level, Quality of Life, and Disability

In this study, the authors examined the prevalence of chronic widespread musculoskeletal pain (CWP) in patients who were undergoing PSG for suspected OSAS. They found that 41 of the 74 patients (55%) had CWP. Female patients had a greater risk of CWP than male patients. Female OSAS patients with CWP had higher pain levels, greater disability levels, higher BMIs and a lower quality of life.

http://www.ncbi.nlm.nih.gov/pubmed/26504332

The Effects of Continuous Positive Airway Pressure on Postoperative Outcomes in Obstructive Sleep Apnea Patients Undergoing Surgery: A Systematic Review and Meta-Analysis

This review suggests that there is “no significant difference in the postoperative adverse events between CPAP and no-CPAP treatment. Patients using CPAP had significantly lower postoperative AHI and a trend toward shorter LOS. There may be potential benefits in the use of CPAP during the perioperative period”

http://www.ncbi.nlm.nih.gov/pubmed/25899270