Continuous positive airway pressure improves gait control in severe obstructive sleep apnoea: A prospective study

The authors examine the effect of 8 weeks of CPAP treatment on gait (as a cognitive task requiring attention and executive functioning resources) in non-obese patients with severe OSA in a prospective controlled trial. They included 12 severe OSA patients and 10 healthy matched subjects. They assessed spontaneous speed and stride time variability and the Stroop test before and after 8 weeks of CPAP. After CPAP treatment, stride time variability was significantly improved and cognitive performance under dual task was also improved. These results suggest using gait as a biomarker of OSA brain consequences.