Comparison of genioglossus muscle activity and efficiency of dexmedetomidine or propofol during drug-induced sleep endoscopy in patients with obstructive sleep apnea/hypopnea syndrome.

The purpose of this study was to evaluate the hemodynamic and respiratory effects of dexmedetomidine vs. propofol in patients with OSAHS during the drug-induced sleep endoscopy (DISE), while simultaneously analyzing the electromyography of genioglossus muscle. The study included 50 patients with OSAHS, who were subjected to DISE with simultaneous polygraphic cardiorespiratory measurement and electromyography of the genioglossus muscle. Patients undergoing DISE received either propofol or dexmedetomidine. A greater worsening of the cardio-respiratory basal values was noted after sleep induction with Propofol and same results were obtained confronting EMG of genioglossus muscle data.