Changing Faces of OSA: Treatment Effects by Cluster Designation in the Icelandic Sleep Apnea Cohort

Distinct clinical phenotypes of obstructive sleep apnea (OSA) have been identified: Disturbed Sleep, Minimally Symptomatic, and Sleepy phenotypes. This study examined relationships between changes in symptoms and PAP adherence. It proved that OSA treatment response patterns differed by initial clinical phenotype and PAP adherence. Individuals with insomnia-related symptoms may require additional targeted therapy for these complaints, emphasizing the need for a personalized approach to management.

https://www.ncbi.nlm.nih.gov/pubmed/29301021