Cardiac troponin values in patients with acute coronary syndrome and sleep apnea A pilot study

The authors compared peak cardiac troponin I (cTnI) levels in patients with OSA vs. patients without OSA who were admitted for an episode of acute coronary syndrome (ACS). They included 89 patients with OSA and 38 patients without OSA with a median AHI of 32. They reported that the peak cTnI was significantly higher in patients without OSA vs. with OSA. The multivariable linear regression analysis of the relationship between peak cTnI level and patient group, age, sex and type of ACS showed that the presence of OSA significantly contributed to the peak cTnI level. These results suggest that OSA – and intermittent hypoxia – has a protective effect in the context of myocardial infarction injury.