Bottom-Up and Top-Down Mechanisms of General Anesthetics Modulate Different Dimensions of Consciousness

Authors: Mashour GA, Hudetz AG.

A very elegant review on the controversy of the precise mechanisms of anesthetic-induced unconsciousness and how levels and contents of consciousness interact to generate subjective experience and what this implies for the mechanisms of anesthetic-induced unconsciousness.

https://www.ncbi.nlm.nih.gov/pubmed/28676745