This study shows promises of using extracellular lactate concentration as a reliable sleep/wake biomarker.
Monthly Archives: November 2012
Identification of a Dopamine Pathway That Regulates Sleep and Arousal in Drosophila
Hypnotic Hypersensitivity to Volatile Anesthetics and Dexmedetomidine in Dopamine β-Hydroxylase Knockout Mice
GABAergic Inhibition of Histaminergic Neurons Regulates Active Waking but Not the Sleep-Wake Switch or Propofol-Induced Loss of Consciousness
This work provides more questions to the role of propofol in entering sleep circuitry. It suggests that a primary function of GABAA receptor-mediated inhibition is to dampen vigilant arousal and it does not appear to influence the loss of consciousness associated with either natural sleep or propofol-induced anesthesia.